性别： 女
职称： 讲师
最高学历、学位： 博士
毕业院校： 中国科学院大学
从事专业： 动物营养与饲料科学
联系电话： 13387542977
E-mail: zhangqian870305@126.com
研究方向
1.猪的肠道免疫代谢与营养调控
2.新型饲料添加剂的开发与应用
教育经历
1．2013/09–2017/12，中国科学院大学，武汉病毒研究所，博士，导师:石正丽
2．2010/09–2013/06，华中农业大学，动物医学院，硕士，导师:吴斌
3．2006/09–2010/06，河南农业大学，牧医工程学院，学士
工作经历
1．2018/07-至今，武汉轻工大学，动物科学与营养工程学院，讲师
2．2015/11-2016/11，杜克-新加坡国立大学医学院，新发传染病系，博士
科研项目
1．湖北省教育厅，青年人才项目，Q20191606，白藜芦醇对PEDV感染的影响及免疫机制研究，2019-01至2020-12，2万元，已结题，主持
代表性论文
1．Zhang Qian, Liu Wenkai, Li Qian, Zeng Yitong, Wu Mengjun, Wu Tao, Guo Shuangshuang, Wang Lei, Zhao Di, Yi Dan, Hou Yongqing, Protective effects and mechanisms of N-acetylcysteine on indomethacin-induced intestinal injury in a porcine model. Ecotoxicol Environ Saf. 2023,262:115173.
2．Zhang Qian,Li Peng, Li Hanbo, Yi Dan, Guo Shuangshuang, Wang Lei, Zhao Di, Wang Chao, Wu Tao, Hou Yongqing, Multifaceted Effects and Mechanisms of N‐Acetylcysteine on Intestinal Injury in a Porcine Epidemic Diarrhea Virus‐Infected Porcine Model, Molecular Nutrition & Food Research, 2022, 66(24): 2200369
3．Zhang Qian, Deng Cuifang, Peng Meng, Li Chengcheng, Teng Yi, Guo Shuangshuang, Wu Tao, Yi Dan, Hou Yongqing, Integration of transcriptomic and proteomic analyses reveals protective mechanisms of N-acetylcysteine in indomethacin-stimulated enterocytes, The Journal of Nutritional Biochemistry, 2022, 112: 109231
4．Zhang Qian, Yi Dan, Ji Changzheng, Wu Tao, Wang Manli, Guo Shuangshuang, Wang Lei, Zhao Di, Hou Yongqing, Monolaurin confers a protective effect against porcine epidemic diarrhea virus infection in piglets by regulating the interferon pathway, Frontiers in Immunology, 2022, 12(7974-76)
5．Zhang Qian, Zhang Lijuan, Lyu Yang, Shi Yutao, Zhu Liangyun, Zhang Min, Zhao Yuyan, Zhao Di, Wang Lei, Yi Dan, Hou Yongqing, Wu Tao, Dietary supplementation of Lactobacillus zeae regulated the gut microbiome in piglets infected with enterotoxi-genic Escherichia coli. Czech J. Anim. Sci, 2022, 67: 27-38.
6．Zhang Qian, Wu Tao, Li Siyuan, Meng Yuxuan, Tan Zihan, Wu Mengjun, Yi Dan, Wang Lei, Zhao Di, Hou Yongqing, Protective Effect of Zinc Oxide and Its Association with Neutrophil Degranulation in Piglets Infected with Porcine Epidemic Diarrhea Virus, Oxidative Medicine and Cellular Longevity, 2021, 2021: 0-3055810
7．Zhang Qian, Hou Yongqing, Bazer W Fuller, He Wenliang, Posey A Erin, Wu Guoyao, Amino Acids in Swine Nutrition and Production, Advances in Experimental Medicine and Biology, 2021, 1285: 81-107
8．Wu Tao#,Zhang Qian# (共同第一作者), Xu Haiwang, Li Peng, Zhao Di, Wang Lei, Yi Dan, Hou Yongqing, Protective effects of α-terpineol and Bacillus coagulans on intestinal function in weaned piglets infected with a recombinant Escherichia coli expressing heat-stable enterotoxin STa. Front Vet Sci. 2023,10:1118957.
9．Wu Mengjun#,Zhang Qian#(共同第一作者), Yi Dan#, Wu Tao, Chen Hongbo, Guo Shuangshuang, Li Siyuan, Ji Changzheng, Wang Lei, Zhao Di, Hou Yongqing, Wu Guoyao, Quantitative Proteomic Analysis Reveals Antiviral and Anti-inflammatory Effects of Puerarin in Piglets Infected with Porcine Epidemic Diarrhea Virus., Frontiers in Immunology, 2020, 11(169).
10．Wu Mengjun#, Yi Dan#,Zhang Qian#(共同第一作者), Wu Tao, Yu Kui, Peng Meng, Wang Lei, Zhao Di, Hou Yongqing, Wu Guo. Puerarin enhances intestinal function in piglets infected with porcine epidemic diarrhea virus. Sci Rep. 2021,11(1):6552.
11．Aaron T Irving,Qian Zhang, Pui-San Kong, Katarina Luko, Pritisha Rozario, Ming Wen, Feng Zhu, Peng Zhou, Justin H J Ng, Radoslaw M Sobota, Lin-Fa Wang, Interferon regulatory factors IRF1 and IRF7 directly regulate gene expression in bats in response to viral infection. Cell Reports, 2020, 33(5): 108345.
12．Matae Ahn, Danielle E. Anderson,Qian Zhang, Chee Wah Tan, Beng Lee Lim, Katarina Luko, Ming Wen, Wan Ni Chia, Shailendra Mani, Loo Chien Wang, Justin Han Jia Ng, Radoslaw M. Sobota, Charles-Antoine Dutertre, Florent Ginhoux, Zhengli Shi, Aaron T. Irving, Lin-Fa Wang, Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Nature Microbiology, 2019, 4(5): 789-799.
13．Qian Zhang, Leiping Zeng, Peng Zhou, Aaron T. Irving, Shang Li, Zhengli Shi, Linfa Wang, IFNAR2-dependent gene expression profile induced by IFN-α in Pteropus alecto bat cells and impact of IFNAR2 knockout on virus infection. PLoS One, 2017, 12(8): e0182866.
14．Qian Zhang, Ruiming Hu, Xibiao Tang, Chenglong Wu, Qigai He, Zhanqin Zhao, Huanchun Chen, Bin Wu, Occurrence and investigation of enteric viral infections in pigs with diarrhea in China. Arch Virol, 2013, 158(8): 1631-1636.
15．Qian Zhang, Ruiming Hu, Junyong Hu, Hua He, Xibiao Tang, Meilin Jin, Huanchun Chen, Bin Wu, aroA deleted Bordetella bronchiseptica inspiring robust mucosal immune response and provide full protection against intranasal challenge, 2013, 94(1): 55-61
