首页  -  师资队伍  -  专家名师  -  正文

侯永清教授

时间:2015-12-17    作者:     浏览次数:

系所:动物科学与营养工程学院

职称:教授(二级)

最高学历、学位:博士

毕业院校:中国农业大学

从事专业:动物营养与饲料科学

E-mailhouyq@aliyun.com

 

个人简介

侯永清,男,中共党员,博士,教授(二级),博士生导师。现任武汉轻工大学党委常委、副校长。国家“万人计划”百千万工程领军人才,“新世纪百千万人才工程”国家级人选,全国农业科研杰出人才,享受国务院特殊津贴专家,湖北省高端人才引领培养计划第一层次人选。教育部动物生产类教学指导委员会委员、中国粮油学会副理事长、中国畜牧兽医学会动物营养学分会常务理事,湖北省畜牧兽医学会副理事长,《动物营养学报》、《中国畜牧杂志》、《Journal of Animal Science and Biotechnology》、《Journal of Nutritional Biochemistry》和《Amino Acids》等杂志编委。

侯永清教授团队合作意识和管理能力强,在科研平台与学科建设方面也做出了重要贡献。主持建设了教育部农副产品蛋白质饲料资源工程研究中心、农业部饲料资源与加工科学观测实验站、湖北省动物营养与肠道健康国际科技合作基地、动物营养与饲料科学湖北省重点实验室、湖北省饲料工程技术研究中心和动物营养与饲料科学湖北省重点学科,主持组建了动物营养与饲料安全湖北省协同创新中心。主持了国家973计划课题、国家自然科学基金联合基金重点项目等国家及省部级纵向科研项目70余项;获国家科技进步奖二等奖1项,湖北省技术发明奖1项,湖北省和湖南省科技进步奖一等奖各1项,湖北省科技进步奖二等奖3项和三等奖2项,湖北省高校教学成果一等奖2项;在国内外学术期刊及会议上发表论文300余篇,其中SCI收录论文160余篇(H指数53);主编著作2部,参编7部;获国家发明专利40项,完成省部级鉴定(评价)成果11项。主持建设湖北省属高校优势特色学科群(生物农业)1个、国家级特色专业1个和国家一流专业建设点1个、国家卓越农林人才教育培养计划改革试点项目(动物科学)1项、省级精品课程2门。培养毕业硕士研究生63名。其领导的科研团队具有良好的创新能力,曾入选“湖北省自然科学基金计划创新群体”、“湖北省高等学校优秀中青年科技创新团队”和“全国农业科研创新团队”。

侯永清教授积极投身于科技成果转化,开发出系列安全环保型饲料添加剂,获得国家饲料添加剂新产品证书一个,提高畜禽生产性能和抗病力、减少抗生素的使用及养殖污染物排放,研究成果在国内三十余家大型企业集团实现了产业化,相关产品辐射到全球20个国家和地区,产生较大的经济和社会效益,先进事迹多次被China Daily、科技日报、湖北日报所报道。

 

教育经历

1981.09-1985.07 华中农业大学(本科)畜牧

1985.09-1988.07 华中农业大学(硕士)动物营养与饲料科学

1996.09-1999.07 中国农业大学(博士)动物营养与饲料科学

 

工作经历

1988.07-1988.12,原商业部武汉粮科所,技术员,助工

1990.04-2001.12,武汉工业学院饲料科学系,助教、讲师、副教授

2002.01-2014.11,武汉轻工大学动物科学与营养工程学院,教授、系副主任、系主任、院长

2008.10.6-2009.3.26,日本东北大学,访问教授

2013.12.17-2014.6.17,美国德克萨斯农工大学,访问学者

2014.12-现在,武汉轻工大学,副校长

 

研究领域

动物分子营养   仔猪营养与肠道健康

 

科研成果

A著作类

水生动物营养与饲料学

饲料分析与检测

仔猪营养学

鱼类营养与饲料配方技术

猪氨基酸营养与代谢

Nutritional and Physiological Functions of Amino Acids in Pigs

B论文类(部分)

1.Zhang Q, Deng C, Peng M, Li C, Teng Y, Guo S, Wu T, Yi D*,Hou YQ*(2023) Integration of transcriptomic and proteomic analyses reveals protective mechanisms of N-acetylcysteine in indomethacin-stimulated enterocytes. J Nutr Biochem.112:109231.

2.Wu T, Zhang Q, Xu HW, Li P, Zhao D, Wang L, Yi D,Hou YQ*(2023) Protective effects of α-terpineol and Bacillus coagulans on intestinal function in weaned piglets infected with a recombinant Escherichia coli expressing heat-stable enterotoxin STa. Front Vet Sci. 10:1118957.

3.Zhang YY†, Li Q†, Wang ZX, Dong Y, Yi D, Wu T, Wang L, Zhao D,Hou YQ*. Dietary supplementation with a complex of cinnamaldehyde, carvacrol, and thymol negatively affects the intestinal function in LPS-challenged piglets. Front Vet Sci. 2023, 10:1098579.

4.Zhang YY†, Tian JJ†, Wang C†, Wu T, Yi D, Wang L, Zhao D,Hou YQ*. N-Acetylcysteine Administration Improves the Redox and Functional Gene Expression Levels in Spleen, Mesenteric Lymph Node and Gastrocnemius Muscle in Piglets Infected with Porcine Epidemic Diarrhea Virus. Animals (Basel). 2023,13(2):262.

5.Zhang Q, Yi D, Ji CZ, Wu T, Wang M, Guo SS, Wang L, Zhao D,Hou YQ*(2022) Monolaurin confers a protective effect against porcine epidemic diarrhea virus infection in piglets by regulating the interferon pathway. Front Immunol. 12:797476.

6.Zhang YY, Yi D, Xu HW, Tan ZH, Meng YX, Wu T, Wang L, Zhao D,Hou YQ* (2022)Dietary supplementation with sodium gluconate improves the growth performance and intestinal function in weaned pigs challenged with a recombinantEscherichia coli strain. BMC Vet Res. 6, 18(1): 303.

7.Zhang Q, Li P, Li HB, Yi D, Guo SS, Wang L, Zhao D, Wang C, Wu T*,Hou YQ* (2022) Multifaceted effects and mechanisms of N-acetylcysteine on intestinal injury in a porcine epidemic diarrhea virus-infected porcine model. Mol Nutr Food Res. e2200369.

8.Wang HY, Li CC, Peng M, Wang L, Zhao D, Wu T, Yi D*,Hou YQ*, Wu G (2021) N-Acetylcysteine improves intestinal function and attenuates intestinal autophagy in piglets challenged with β-conglycinin. Sci Rep. 1(1):1261.

9.Wu MJ, Yi D, Zhang Q, Wu T, Yu K, Peng M, Wang L, Zhao D,Hou YQ*, Wu G (2021) Puerarin enhances intestinal function in piglets infected with porcine epidemic diarrhea virus. Scientific Reports. 11: 6552

10.Wu T, Lyu Y, Li X, Wu M, Yu K, Li S, Ji C, Zhang Q, Zhang Y, Zhao D, Yi D,Hou YQ* (2021) Impact of N-acetylcysteine on the gut microbiota in the piglets infected with porcine epidemic diarrhea virus. Front Vet Sci. 7:582338.

11.Zhang Y, Wu T, Chen ZQ, Meng YX, Zhu ZK, Wang Q, Tian JJ, Yi D, Wang L, Zhao D,Hou YQ* (2021) Dietary supplementation with enterococcus faecium R1 attenuates intestinal and liver injury in piglets challenged by lipopolysaccharide. Animals. 11:1424.

12.Zhang Q, Wu T, Li SY, Meng YX, Tan ZH, Wu MJ, Yi D, Wang L, Zhao D,Hou YQ* (2021) Protective effect of zinc oxide and its association with neutrophil degranulation in piglets infected with porcine epidemic diarrhea virus. Oxid Med Cell Longev. 2021:3055810.

13.Wu T, Shi YT, Zhang YY, Zhang M, Zhang LJ, Ma ZP, Zhao D, Wang L, Yu H,Hou YQ*, Gong J*(2021) Lactobacillus rhamnosus LB1 alleviates enterotoxigenic escherichia coli-induced adverse effects in piglets by improving host immune response and anti-oxidation stress and restoring intestinal integrity. Front Cell Infect Microbiol. 11:724401.

14.Zhang Q,Hou YQ*, Bazer FW, He W, Posey EA, Wu G (2021) Amino acids in swine nutrition and production. Adv Exp Med Biol. 1285:81-107.

15.Fu S, Liu J, Xu J, Zuo S, Zhang Y, Guo L, Qiu Y, Ye C, Liu Y, Wu Z,Hou YQ, Hu CA (2020) The effect of baicalin on microRNA expression profiles in porcine aortic vascular endothelial cells infected by Haemophilus parasuis. Mol Cell Biochem. 472(1-2):45-56.

16.Fu S, Yin R, Zuo S, Liu J, Zhang Y, Guo L, Qiu Y, Ye C, Liu Y, Wu Z,Hou YQ, Hu CA (2020) The effects of baicalin on piglets challenged with Glaesserella parasuis. Vet Res. 51(1):102.

17.Guo L, Liu J, Zhang Y, Fu S, Qiu Y, Ye C, Liu Y, Wu Z,Hou YQ, Hu CA (2020) The effect of baicalin on the expression profiles of long non-coding RNAs and mRNAs in porcine aortic vascular endothelial cells infected withhaemophilus parasuis. DNA Cell Biol. 39(5):801-815.

18.Guo SS, Xv J, Li Y, Bi Y,Hou YQ, Ding B (2020) Interactive effects of dietary vitamin K3andBacillus subtilisPB6 on the growth performance and tibia quality of broiler chickens with sex separate rearing. Animal. 14:1-9.

19.Guo SS, Zhang YK, Cheng Q, Xv JY,Hou YQ, W XF, Du EC, Ding BY (2020) Partial substitution of fermented soybean meal for soybean meal influences the carcass traits and meat quality of broiler chickens. Animals. 10(2):225.

20.Hou YQ, Hu S, Li X, He W, Wu G (2020) Amino acid metabolism in the liver: Nutritional and physiological significance. Adv Exp Med Biol. 1265:21-37.

21.Li C, Peng M, Liao M, Guo S,Hou YQ, Ding B, Wu T, Yi D (2020) Effects of N-acetylcysteine on the energy status and antioxidant capacity in heart and liver of cold-stressed broilers. Asian-Australas J Anim Sci. 33(9):1444-1454.

22.Wu MJ, Zhang Q, Yi D, Wu T, Chen HB, Guo SS, Li SY, Ji CZ, Wang L, Zhao D,Hou YQ*, Wu G (2020)Quantitative proteomic analysis reveals antiviral and anti-inflammatory effects of puerarin in piglets infected with porcine epidemic diarrhea virus. Front Immunol. 11:169.

23.Wu T, Li K, Lyu Y, Yi D, Zhao D, Wang L, Ding BY,Hou YQ*, Wu G (2020) Trilactic glyceride regulates lipid metabolism and improves gut function in piglets. Front Biosci (Landmark Ed). 25:1324-1336.

24.Cheng Q, Xia Y, Yi D,Hou YQ, Duan R, Guo SS*, Ding BY (2019) The intestinal cinnamaldehyde release and antioxidative capacity of broiler chickens fed diets supplemented with coated oleum cinnamomi. J Appl Poultry Res. 28(4):1058-1068

25.Fu S, Zhao W, Xiong C, Guo L, Guo J, Qiu Y, Hu CA, Ye C, Liu Y, Wu Z,Hou YQ(2019) Baicalin modulates apoptosis via RAGE, MAPK, and AP-1 in vascular endothelial cells duringHaemophilus parasuisinvasion. Innate Immun. 25(7):420-432.

26.Fu S, Zhuang F, Guo L, Qiu Y, Xiong J, Ye C, Liu Y, Wu Z,Hou YQ, Hu CA (2019) Effect of baicalin-aluminum complexes on fecal microbiome in piglets. Int J Mol Sci. 20(10):2390.

27.Hou YQ,He W,Hu S,Wu G(2019) Composition of polyamines and amino acids in plant-source foods for human consumption.Amino Acids. 51(8):1153-1165.

28.Wu Z,Hou YQ, Dai Z, Hu CA, Wu G (2019) Metabolism, nutrition, and redox signaling of hydroxyproline. Antioxid Redox Signal. 30(4):674-682.

29.Wu Z,Hou YQ,Dai Z,Hu CA,Wu G(2019) Metabolism, nutrition, and redox signaling of hydroxyproline.Antioxid Redox Signal.30(4):674-682.

30.Ye C, Li R, Xu L, Qiu Y, Fu S, Liu Y, Wu Z,Hou YQ, Hu CA (2019) Effects of Baicalin on piglet monocytes involving PKC-MAPK signaling pathways induced by Haemophilus parasuis. BMC Vet Res. 15(1):98.

31.Zhang J, Xu X, Zhu H, Wang Y,Hou YQ, Liu Y (2019) Dietary fish oil supplementation alters liver gene expressions to protect against LPS-induced liver injury in weanling piglets. Innate Immun. 25(1):60-72.

32.Zhang JM, He WL, Yi D, Zhao D, Song Z,Hou YQ*, Wu G (2019) Regulation of protein synthesis in porcine mammary epithelial cells by L‑valine. Amino Acids.51(4):717-726

33.Zhang JM, Zhao D, Yi D, Wu MJ, Chen HB, Wu T, Zhou J, Li P,Hou YQ*, Wu G (2019) Microarray analysis reveals the inhibition of intestinal expression of nutrient transporters in piglets infected with porcine epidemic diarrhea virus. Sci Rep. 9:19798

34.Hou YQ,Li X,Dai Z,Wu Z,Bazer FW,Wu G(2018) Analysis of glutathione in biological samples by hplc involving pre-column derivatization with o-phthalaldehyde.Methods Mol Biol.1694:105-115.

35.Wu T,Lv Y,Li XN,Zhao D,Yi D,Wang L,Li P,Chen HB,Hou YQ*,Gong J,Wu G(2018) Establishment of a recombinantEscherichia coli-induced piglet diarrhea model.Front Biosci (Landmark Ed).23:1517-1534.

36.Yi D,Li B,Hou YQ*,Wang L,Zhao D,Chen H,Wu T,Zhou Y,Ding B,Wu G(2018) Dietary supplementation with an amino acid blend enhances intestinal function inpiglets.Amino Acids.50:1089-1100.

37.Yi D,Liu W,Hou YQ*,Wang L,Zhao D,Wu T,Ding B,Wu G(2018) Establishment of a porcine model of indomethacin-induced intestinal injury.Front Biosci (Landmark Ed).23:2166-2176.

38.Hou YQ, Wu G (2018) L‑Glutamate nutrition and metabolism in swine. Amino Acids. 50(11):1497–1510.

39.Wu T, Zhang Y, Lv Y, Li P, Yi D, Wang L, Zhao D, Chen HB, Gong J,Hou YQ*(2018) Beneficial impact and molecular mechanism of bacillus coagulans on piglets’ intestine. Int J Mol Sci. 19(7):2084-2100.

40.Hou YQ,Wu G(2018)Nutritionally essential amino acids.Adv Nutr.9(6):849-851.

41.Yi D, Fang QH,Hou YQ*, Wang L, Xu HW, Wu T, Gong J, Wu G (2018) Dietary supplementation with oleum cinnamomi improves intestinal functions in piglets. Int J Mol Sci. 19:1284-1297.

42.Wu T,Li K,Yi D,Wang L,Zhao D,Lv Y,Zhang L,Chen H,Ding B,Hou YQ*,Wu G(2018) Dietary supplementation with trihexanoin enhances intestinal function of weaned piglets. Int J Mol Sci. 19:3277.

43.Lv Y,Li X,Zhang L,Shi Y,Du L,Ding B,Hou YQ,Gong J,Wu T(2018) Injury and mechanism of recombinant E. coli expressing STa on piglets colon.J VetMed Sci.80(2): 205-212.

44.Lv Y, Kang P, Zhang L, Li XN, Wang L, Zhao D, Yi D, Ding BY, Chen HB,Hou YQ, Wu T (2018). Generation of epidermal growth factor and green fluorescent protein coexpressing Lactobacillus acidophilus and its effect on intestinal histology improvement in mature LPS-challenged mice.Thai J Vet Med. 48(2):147-156.

45.Guo SS, Cheng Q, Li YH, Duan R,Hou YQ, Yi D, Ding BY (2018) Effects of dietary coated-oleum cinnamomi supplementation on the immunity and intestinal integrity of broiler chickens. Anim Sci J. 89(11): 1581-1590

46.Wu G,Bazer FW,Johnson GA,Hou YQ(2018) BOARD-INVITED REVIEW: Arginine nutrition and metabolism in growing gestating, and lactating swine.J Anim Sci.96(12):5035-5051.

47.Bedford A, Yu H, Hernandez M, Squires EJ, Leeson S,Hou YQ, Gong J (2018) Response of Ross 308 and 708 broiler strains in growth performance and lipid metabolism to diets containing tributyrate glycerides.Can J Anim Sci. 98(1):98-108.

48.Fu S,Liu H,Xu L,Qiu Y,Liu Y,Wu Z,Ye C,Hou YQ,Hu CA(2018) Baicalin modulates NF-κB and NLRP3 inflammasome signaling in porcine aortic vascularendothelial cells infected by haemophilus parasuis causing glässer's disease.Sci Rep.8(1):807.

49.Robinson K,Ma X,Liu Y,Qiao S,Hou YQ,Zhang G(2018) Dietary modulation of endogenous host defense peptide synthesis as an alternative approach to in-feed antibiotics.Anim Nutr.4(2):160-169.

50.Zhu H,Wang H,Wang S,Tu Z,Zhang L,Wang X,Hou YQ,Wang C,Chen J,Liu Y(2018) Flaxseed oil attenuates intestinal damage and inflammation by regulating necroptosis and TLR4/NOD signaling pathways following lipopolysaccharide challenge in a piglet model.Mol Nutr Food Res.62(9):e1700814.

51.Kang P,Liu Y,Zhu H,Zhang J,Shi H,Li S,Pi D,Leng W,Wang X,Wu H,Hou YQ(2018) The effect of dietary asparagine supplementation on energy metabolism in liver of weaning pigs when challenged with lipopolysaccharide.Asian-Australas J Anim Sci.31(4):548-555.

52.Yang X,Yin F,Yang Y,Lepp D,Yu H,Ruan Z,Yang C,Yin Y,Hou YQ,Leeson S,Gong J(2018) Dietary butyrate glycerides modulate intestinal microbiota composition and serum metabolites in broilers.Sci Rep.8(1):4940.

53.Fu S,Liu H,Chen X,Qiu Y,Ye C,Liu Y,Wu Z,Guo L,Hou YQ,Hu CA(2018) Baicalin inhibits haemophilus parasuis-induced high-mobility group box 1 release during inflammation.Int J Mol Sci.19(5). pii:E1307.

54.Fu S,Guo J,Li R,Qiu Y,Ye C,Liu Y,Wu Z,Guo L,Hou YQ,Hu CA(2018) Transcriptional profiling of host cell responses to virulent haemophilus parasuis: New insights into pathogenesis.Int J Mol Sci.19(5). pii:E1320.

55.Xu X,Wang X,Wu H,Zhu H,Liu C,Hou YQ,Dai B,Liu X,Liu Y(2018) Glycine Relieves Intestinal Injury by Maintaining mTOR Signaling and Suppressing AMPK, TLR4, and NOD Signaling in Weaned Piglets after Lipopolysaccharide Challenge.Int J Mol Sci.19(7). pii:E1980.

56.Qin Q,Xu X,Wang X,Wu H,Zhu H,Hou YQ,Dai B,Liu X,Liu Y(2018) Glutamate alleviates intestinal injury, maintains mTOR and suppresses TLR4 and NOD signaling pathways in weanling pigs challenged with lipopolysaccharide.Sci Rep.8(1):15124.

57.Hou YQ, Wu G (2017) Nutritionally nonessential amino acids: A misnomer in nutritional sciences.Adv Nutr.8:137-139.

58.Yi D,Hou YQ, Mei HM, Wang L, Hu CAA, Wu G (2017) β‑Conglycinin enhances autophagy in porcine enterocytes. Amino Acids. 49(1):203-207

59.Wang L, Zhou J,Hou YQ*, Yi D, Ding BY, Xie JQ, Zhang Y, Chen HB, Wu T, Zhao D, Hu CAA, Wu G (2017) N-Acetylcysteine supplementation alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus. Amino Acids. 49:1931-1943.

60.Yi D,Hou YQ*, Xiao H, Wang L, Zhang Y, Chen HB, Wu T, Ding BY, Hu CAA, Wu G (2017) N-Acetylcysteine improves intestinal function in lipopolysaccharides-challenged piglets through multiple signaling pathways. Amino Acids. 49:1915-1929.

61.Hou YQ, Wu Z, Dai Z, Wang G, Wu G (2017) Protein hydrolysates in animal nutrition: Industrial production, bioactive peptides and functional significance. J Anim Sci Biotechnol. 8:24

62.Zhao D,Wu T,Yi D,Wang L,Li P,Zhang J,Hou YQ*,Wu G(2017) Dietary Supplementation with lactobacillus casei alleviates lipopolysaccharide-induced liver injury in a porcine model.Int J Mol Sci. 18(12):2535.

63.Liu Y,Wang X,Leng W,Pi D,Tu Z,Zhu H,Shi H,Li S,Hou YQ,Hu CA(2017) Aspartate inhibits LPS-induced MAFbx and MuRF1 expression in skeletal muscle in weaned pigs by regulating Akt, AMPKα and FOXO1.Innate Immun.23(1):34-43.

64.Wu F,Xiong X,Yang H,Yao K,Duan Y,Wang X,Tan B,Li T,Xiao L,Hou YQ,Wu G,Yin Y(2017) Expression of proteins in intestinal middle villus epithelial cells of weanling piglets.Front Biosci (Landmark Ed).22:539-557.

65.Guo S,Duan R,Wang L,Hou YQ,Tan L,Cheng Q,Liao M,Ding B(2017) Dietary α-ketoglutarate supplementation improves hepatic and intestinal energy status and anti-oxidative capacity of Cherry Valley ducks.Anim Sci J.88(11):1753-1762.

66.Liu Y,Wang X,Hou YQ,Yin Y,Qiu Y,Wu G,Hu CA(2017) Roles of amino acids in preventing and treating intestinal diseases: recent studies with pigmodels.Amino Acids.49(8):1277-1291.

67.Zhu H,Pi D,Leng W,Wang X,Hu CA,Hou YQ,Xiong J,Wang C,Qin Q,Liu Y(2017) Asparagine preserves intestinal barrier function from LPS-induced injury and regulatesCRF/CRFR signaling pathway.Innate Immun.23(6):546-556.

68.Kang P,Wang X,Wu H,Zhu H,Hou YQ,Wang L,Liu Y(2017) Glutamate alleviates muscle protein loss by modulating TLR4, NODs, Akt/FOXO and mTORsignaling pathways in LPS-challenged piglets.PLoS One.12(8):e0182246.

69.Jiang Q,Liu G,Wang X,Hou YQ,Duan Y,Wu G,Yin Y,Yao K(2017) Mitochondrial pathway is involved in the protective effects of alpha-ketoglutarate on hydrogenperoxide induced damage to intestinal cells.Oncotarget.8(43):74820-74835.

70.Yi D,Hou YQ*, Wang L, Zhao D, Ding BY, Wu T, Chen HB, Liu YL, Kang P, Wu G (2016) Gene expression profiles in the intestine of lipopolysaccharide-challenged piglets.Front Biosci (Landmark Ed). 21:487-501.

71.Yi D,Hou YQ*, Wang L, Long MH, Hu S, Mei HM, Yan LQ, Hu CAA, Wu G (2016) N-Acetylcysteine stimulates protein synthesis in enterocytes independently of glutathione synthesis. Amino Acids. 48(2):523-533.

72.Hou YQ,Yao K,Yin YL,Wu G(2016) Endogenous synthesis of amino acids limits growth, lactation, and reproduction in animals.Adv Nutr.7(2):331-342.

73.Wang L, Yi D,Hou YQ*, Ding BY, Li K, Li BC, Zhu HL, Liu YL, Wu G (2016) Dietary supplementation with a-ketoglutarate activates mTOR signaling and enhances energy status in skeletal muscle of lipopolysaccharide-challenged piglets. J Nutr. 146:1514-1520.

74.Hou YQ,Hu S,Jia S,Nawaratna G,Che D,Wang F,Bazer FW,Wu G(2016) Whole-body synthesis of L-homoarginine in pigs and rats supplemented with L-arginine. Amino Acids.48(4):993-1001.

75.Yin J, Ren W, Yang G, Duan J, Huang X, Fang R, Li C, Li T, Yin Y,Hou YQ, Kim SW, Wu G (2016)L-Cysteine metabolism and its nutritional implications.Mol Nutr Food Res. 60(1):134-46.

76.Duan Y, Li F, Li Y, Tang Y, Kong X, Feng Z, Anthony TG, Watford M,Hou YQ, Wu G, Yin Y (2016)The role of leucine and its metabolites in protein and energy metabolism.Amino Acids. 48(1):41-51.

77.He X, Duan Y, Yao K, Li F,Hou YQ, Wu G, Yin Y (2016)β-Hydroxy-β-methylbutyrate, mitochondrial biogenesis, and skeletal muscle health.Amino Acids. 48(3):653-664.

78.Rezaei R, Wu Z,Hou YQ,Bazer FW,Wu G(2016) Amino acids and mammary gland development: nutritional implications for milk production and neonatal growth.J Anim Sci Biotechnol.7:20.

79.Ye C, Li S, Yao W, Xu L, Qiu Y, Liu Y, Wu Z,Hou YQ(2016)The anti-inflammatory effects of baicalin through suppression of NLRP3 inflammasomepathway in LPS-challenged piglet mononuclear phagocytes.Innate Immun. 22(3):196-204.

80.Wu Z,Hou YQ, Hu S, Bazer FW, Meininger CJ, McNeal CJ, Wu G (2016)Catabolism and safety of supplemental L-arginine in animals.Amino Acids. 48(7):1541-52

81.Jiang Q,He L,Hou YQ,Chen J,Duan Y,Deng D,Wu G,Yin Y,Yao K(2016) Alpha-ketoglutarate enhances milk protein synthesis by porcine mammary epithelial cells.Amino Acids.48(9):2179-88.

82.Liu Y,Wang X,Wu H,Chen S,Zhu H,Zhang J,Hou YQ,Hu CA,Zhang G(2016) Glycine enhances muscle protein mass associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing TLR4 and NOD2 signaling in piglets challenged with LPS.Am J Physiol Regul Integr Comp Physiol.311(2):R365-73.

83.Xiong X,Yang H,Hu X,Wang X,Li B,Long L,Li T,Wang J,Hou YQ,Wu G,Yin Y(2016) Differential proteome analysis along jejunal crypt-villus axis in piglets.Front Biosci (Landmark Ed).21:343-63.

84.Yao K,Duan Y,Li F,Tan B,Hou YQ,Wu G,Yin Y(2016) Leucine in Obesity: Therapeutic Prospects.Trends Pharmacol Sci.37(8):714-727.

85.Fu S,Xu L,Li S,Qiu Y,Liu Y,Wu Z,Ye C,Hou YQ,Hu CA(2016) Baicalin suppresses NLRP3 inflammasome and nuclear factor-kappa B (NF-κB) signaling during Haemophilus parasuis infection.Vet Res.47(1):80.

86.Yin F, Yu H, Lepp D, Shi X, Yang X, Hu J, Leeson S, Yang C, Nie S,Hou YQ, Gong J (2016) Transcriptome analysis reveals regulation of gene expression for lipid catabolism in young broilers by butyrate glycerides. PLoS One 11(8): e0160751.

87.Hou YQ, Yin YL, Wu G (2015) Dietary essentiality of ‘‘nutritionally non-essential amino acids’’ for animals and humans. Exp Biol Med. 240(8):997-1007.

88.Hou YQ, Jia SC, Nawaratna G, Hu SD, Dahanayaka S, Bazer FW, Wu G (2015) Analysis of L-homoarginine in biological samples by HPLC involving precolumn derivatization with o‑phthalaldehyde and N‑acetyl‑L‑cysteine.Amino Acids. 47(9):2005-2014.

89.Wang L,Hou YQ*, Yi D, Li YT, Ding BY, Zhu HL, Liu J, Xiao H, Wu G (2015) Dietary supplementation with glutamate precursor α-ketoglutarate attenuates lipopolysaccharide-induced liver injury in young pigs.Amino Acids. 47:1309-1318.

90.Hou YQ, Wang L, Yi D, Wu G (2015)N-acetylcysteine and intestinal health: a focus on its mechanism of action.Front Biosci (Landmark Ed).20: 872-891.

91.Wang L,Hou YQ*, Yi, D Ding BY, Zhao D, Wang ZX, Zhu HL, Liu YL, Gong J, Assaad H, Wu G (2015)Beneficial roles of dietary oleum cinnamomi in alleviating intestinal injury.Front Biosci (Landmark Ed). 20: 814-828.

92.Yi D,Hou YQ*,Wang L,Ouyang WJ,Long MH,Zhao D,Ding BY,Liu YL,Wu G(2015) L-Glutamine enhances enterocyte growth via activation of the mTOR signaling pathway independently of AMPK.Amino Acids.47:65-78.

93.Kang P, Liu YL, Zhu HL, Li S, Shi HF, Chen F, Leng WB, Pi DA,Hou YQ, Yi D (2015) The effect of aspartate on the energy metabolism in the liver of weanling pigs challenged with lipopolysaccharide. Eur J Nutr. 54(4):581-588.

94.Yang CB, Chowdhury MAK,Hou YQ, Gong J (2015) Phytogenic compounds as alternatives to in-feed antibiotics: Potentials and challenges in application. Pathogens. 4:137-156.

95.Dahanayaka S, Rezaei R, Porter WW, Johnson GA, Burghardt RC, Bazer FW,Hou YQ, Wu ZL, Wu G (2015) Technical note: Isolation and characterization of porcine mammary epithelial cells. J Anim Sci 93:5186–5193.

96.Ma X,Hou YQ,Dahanayaka S,Satterfield MC,Burghardt RC,Bazer FW,Wu G(2015) Technical note: Isolation and characterization of ovine brown adipocyte precursor cells.J Anim Sci.93(5):2094-2099.

97.Tan B,Xiao H,Xiong X,Wang J,Li G,Yin Y,Huang B,Hou YQ,Wu G(2015) L-Arginine improves DNA synthesis in LPS-challenged enterocytes.Front Biosci (Landmark Ed).20:989-1003

98.Liu Y,Yao WX,Xu J,Qiu YS,Cao FY,Li SL,Yang S,Yang HL,Wu ZY,Hou YQ(2015) The anti-inflammatory effects of acetaminophen and N-acetylcysteine through suppression of NLRP3 inflammasome pathway in lipopolysaccharide-challenged piglet mononuclear phagocytes.Innate Immun.21(6) 587–597.

99.Xiao H, Wu MM, Tan BE, Li TJ , Ren WK, Yin J, Wang J, He QH, Yin YL,Hou YQ(2015) Metabolic profiles in the response to supplementation with composite antimicrobial peptides in piglets challenged with deoxynivalenol. J Anim Sci. 93 (3): 1114-1123.

100.Xiong X, Yang HS, Wang XC, Hu Q, Liu CX, Wu X, Deng D,Hou YQ, Nyachoti CM, Xiao DF (2015) Effect of low dosage of chito-oligosaccharide supplementation on intestinal morphology, immune response, antioxidant capacity, and barrier function in weaned piglets.J Anim Sci93 (3): 1089-1097.

101.Yin J, Ren W,Hou YQ, Wu M, Xiao H, Duan J, Zhao Y, Li T, Yin Y, Wu G, Nyachoti CM (2015)Use of homoarginine for measuring true ileal digestibility of amino acids in food protein.Amino Acids. 47(9):1795-803.

102.Assaad HI,Hou YQ,Zhou L,Carroll RJ,Wu G(2015) Rapid publication-ready MS-Word tables for two-way ANOVA.Springerplus.4:33.

103.Wang SP,Gao YL,Liu G,Deng D,Chen RJ,Zhang YZ,Li LL,Wen QQ,Hou YQ,Feng ZM,Guo ZH(2015) Molecular cloning, characterization and expression of the energy homeostasis-associated gene in piglet.J Zhejiang Univ Sci B.16(6):524-532.

104.Wu H,Liu Y,Pi D,Leng W,Zhu H,Hou YQ,Li S,Shi H,Wang X(2015) Asparagine attenuates hepatic injury caused by lipopolysaccharide in weaned piglets associated with modulation of Toll-like receptor 4 and nucleotide-binding oligomerisation domain proteinsignalling and their negative regulators.Br J Nutr.114(2):189-201.

105.Wang X,Liu Y,Li S,Pi D,Zhu H,Hou YQ,Shi H,Leng W(2015) Asparagine attenuates intestinal injury, improves energy status and inhibits AMP-activatedprotein kinase signalling pathways in weaned piglets challenged with Escherichia colilipopolysaccharide.Br J Nutr.114(4):553-565.

106.Hu CA,Hou YQ, Yi D, Qiu Y, Wu G, Kong X, Yin Y (2015)Autophagy and tight junction proteins inthe intestine and intestinal diseases.Anim Nutr. 1(3):123-127.

107.Wu Z,Hu CA,Wu G,Zhaorigetu S,Chand H,Sun K,Ji Y,Wang B,Dai Z,Walton B,Miao Y,Hou YQ(2015) Intimacy and a deadly feud: the interplay of autophagy and apoptosis mediated by amino acids.Amino Acids.47(10):2089-2099.

108.Li J,Hou YQ,Yi D,Zhang J,Wang L,Qiu H,Ding B,Gong J(2015) Effects of tributyrin on intestinal energy status, antioxidative capacity and immune response to lipopolysaccharide challenge in broilers.Asian-Australas J Anim Sci.28(12):1784-1793.

109.Robinson K, Deng Z,Hou YQ, Zhang G (2015) Regulation of the intestinal barrier function by host defense peptides. Front Vet Sci. 2:57.

110.Zhu HL,Hu LL,Hou YQ,Zhang J,Ding BY(2014) The effects of enzyme supplementation on performance and digestive parameters of broilers fed corn-soybean diets.Poult Sci. 93(7):1704-1712.

111.Yin FG,Farzan A,Wang QC,Yu H,Yin YL,Hou YQ,Friendship RM,Gong J(2014) Reduction of Salmonella enterica serovar typhimurium DT104 infection in experimentally challenged weaned pigs fed a lactobacillus-fermented feed.Foodborne Pathog Dis.11(8):628-634.

112.Yi D,Hou YQ*, Wang L, Ding BY, Yang ZG, Li J, Long MH, Liu YL, Wu G (2014) Dietary N-acetylcysteine supplementation alleviates liver injury in lipopolysaccharide-challenged piglets. Br J Nutr. 111: 46-54.

113.Ruan Z,Liu SQ,Zhou Y,Mi SM,Liu G,Wu X,Yao K,Assaad H,Deng ZY,Hou YQ,Wu G,Yin YL (2014) Chlorogenic acid decreases intestinal permeability and increases expression of intestinal tight junction proteins in weaned rats challenged with LPS. PLoS One. 9(6):e97815.

114.Pi DA, Liu YL, Shi HF, Li S, Odle J, Lin Xi, Zhu HL, Chen F,Hou YQ, Leng WB (2014) Dietary supplementation of aspartate enhances intestinal integrity and energy status in weanling piglets after lipopolysaccharide challenge. J Nutr Biochem. 25(4):456-462.

115.Leng WB, Liu YL, Shi HF, Li S, Zhu HL, Pi DA,Hou YQ, Gong J (2014) Aspartate alleviates liver injury and regulates mRNA expressions of TLR4 and NOD signaling related genes in weaned pigs after lipopolysaccharide challenge. J Nutr Biochem. 25(6):592-599

116.Kang P, Zhang LL,Hou YQ*, Ding BY, Yi D, Wang L, Zhu HL, Liu YL, Yin YL, Wu GY (2014) Effects of L-proline on the growth performance, and blood parameters in weaned lipopolysaccharide (LPS)-challenged pigs. Asian Australas J Anim Sci. 27(8):1150-1156.

117.Hou YQ*,Wang L,Yi D,Ding BY,Chen X,Wang QJ,Zhu HL,Liu YL,Yin YL,Gong J,Wu G(2014) Dietary supplementation with tributyrin alleviates intestinal injury in piglets challenged with intrarectal administration of acetic acid. Br J Nutr. 111(10):1748-1758

118.Gong J, Yin FG,Hou YQ, Yin YL (2014) Review: Chinese herbs as alternatives to antibiotics in feed for swine and poultry production: Potential and challenges in application. Can J Anim Sci. 94:223-241.

119.Hou YQ*, Yi D, Zhao D, Long MH, Ding BY, Wang L, Wu G (2014) Quantitative analysis of transcriptional responses of the porcine small and large intestines to lipopolysaccharide challenge (LB745). FASEB J. 28:LB745.

120.Ren WK,Duan JL,Yin J,Liu G,Cao Z,Xiong X,Chen S,Li TJ,Yin YL,Hou YQ,Wu G(2014) Dietary L-glutamine supplementation modulates microbial community and activates innate immunity in the mouse intestine.Amino Acids.46(10):2403-2413.

121.Hou YQ*, Wang L,YiD,DingBY,YangZG,LiJ,ChenX,QiuYS,WuG(2013)N-acetylcysteine reduces inflammation in the small intestine by regulating redox, EGF and TLR4 signaling.Amino Acids.45:513–522.

122.Zhu HL, Liu YL, Xie XL, Huang JJ,Hou YQ(2013) Effect of L-arginine on intestinal mucosal immune barrier function in weaned pigs after Escherichia coli LPS challenge. Innate Immun. 19(3): 242-252.

123.He LQ,Yang HS,Hou YQ,Li TJ,Fang J,Zhou XH,Yin YL,Wu L,Nyachoti M,Wu G(2013) Effects of dietary L-lysine intake on the intestinal mucosa and expression of CAT genes in weaned piglets. Amino Acids. 45(2):383-391.

124.Ren WK,ZouLX,Ruan Z,Li NZ,Wang Y,Peng YY,Liu G,Yin YL,Li TJ,Hou YQ,Wu G(2013) Dietary L-proline supplementation confers immunostimulatory effects on inactivated Pasteurella multocida vaccine immunized mice.Amino Acids.45(3):555-561.

125.Liu YL, Chen F, Odle J, Lin X, Zhu HL, Shi HF,Hou YQ, Yin JD (2013) Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4 and NOD signaling in weaning piglets after LPS challenge. J Nutr. 143(8):1331-1339.

126.Chen F,Liu YL,Zhu HL,Hong Y,Wu ZF,Hou YQ,Li Q,Ding BY,Yi D,Chen HB (2013) Fish oil attenuates liver injury caused by LPS in weaned pigs associated with inhibition of TLR4 and nucleotide-binding oligomerization domain protein signaling pathways. Innate Immun.19(5):504-515.

127.Blachier F, Wu GY, Yin YL,Hou YQ, Andriamihaja M (2013) Developmental amino acid metabolism in the pig small and large intestine epithelial cells.In: Blachier F, Wu GY and Yin YL (ed)Nutritional and Physiological Functions of Amino Acids in Pigs.New York,pp 59-74.

128.He QH, Yin YL,Hou YQ, Qin GX, Sun H, Liu JH, Liu B, Zheng ZK (2013) Factors that affect amino acid metabolism in pigs.In: Blachier F, Wu GY and Yin YL (ed)Nutritional and Physiological Functions of Amino Acids in Pigs.New York,pp 123-140.

129.Qiu YS, Zhang JW, Liu Y, Ma HW, Cao FY, Xu J,Hou YQ, Xu LY (2013) The combination effects of acetaminophen and N-acetylcysteine on cytokines production and NF-κB activation of lipopolysaccharide-challenged piglet mononuclear phagocytes in vitro and in vivo. Vet Immunol Immunopathol. 152: 381-388.

130.Kang P,Hou YQ, Toms D, Yan ND, Ding BY, Gong J. 2013. Effects of enzyme complex supplementation to a paddy-based diet on performance and nutrient digestibility of meat-type ducks.Asian-Australas J Anim Sci.26 (2): 253-259.

131.Liu YL, Chen F, Li Q, Odle J, Lin X, Zhu HL, Hong Y,Hou YQ, Yi D, Shi HF (2013) Fish oil alleviates activation of hypothalamic-pituitary-adrenal axis associated with inhibition of TLR4 and NOD signaling pathways in weaning pigs after an LPS challenge. J Nutr. 143: 1799-1807.

132.Wang QJ,Hou YQ*, Yi D, Wang L, Ding BY, Chen X, Long MH, Liu YL, Wu G (2013) Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model. BMC Gastroenterol 13: 133.

133.Yin FG, Yin YL,Hou YQ. Synthesis and degradation of proteins in pigs (2013) In: Blachier F, Wu GY and Yin YL (ed) Nutritional and Physiological Functions of Amino Acids in Pigs. New York, pp 109-122.

134.Long MH. Ouyang WJ, Yi D,Hou YQ*, Wu G (2013) N-Acetylcysteine stimulates proliferation and prevents lipopolysaccharide-induced death of intestinal porcine epithelial cells. Amino Acids. 45:583.

135.Hou YQ*, Wang L, Zhang W, Yang ZG, Ding BY, Zhu HL, Liu YL, Qiu YS, Yin YL, Wu GY (2012) Protective effects of N-acetylcysteine on intestinal functions of piglets challenged with lipopolysaccharide. Amino Acids, 43: 1233-1242.

136.YiD,GuLF,DingBY,LiM,Hou YQ*,WangL,GongJ (2012) Effects of dietary silymarin supplementation on growth performance and oxidative status in carassius auratus gibelio. J Anim Vet Adv. 11(18): 3399-3404.

137.Yi D, Wang C, Sun DF,Hou YQ*, Ding BY, Wang L, Gong J (2012) Diet supplementation of silymarin increased the antioxidantive capacity in cumene hydroperoxide-challenged ducks. J Anim Vet Adv. 11(16): 2986-2994.

138.Yao K, Yin YL, Li XL, Xi PB, Wang JJ, Lei J,Hou YQ, Wu G (2012) Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells. Amino Acids. 42(6): 2491-2500.

139.Liu YL, Chen F, Odle J, Lin X, Jacobi SK, Zhu HL, Wu ZF,Hou YQ(2012) Fish oil enhances intestinal integrity and inhibits TLR4 and NOD2 signaling pathways in weaned pigs after LPS challenge. J Nutr. 142(11): 2017-2024.

140.Li Q, Liu YL, Che ZQ, Zhu HL, Meng GQ,Hou YQ, Ding BY, Yin YL, Chen F (2012) Dietary L-arginine supplementation alleviates liver injury caused by Escherichia coli LPS in weaned pigs. Innate Immun. 18(6): 804–814.

141.Kang P, Wang M,Hou YQ*, Yin YL, Ding BY, Zhu HL, Liu YL, Qiu YS,YiD,WangL,GongJ (2012) Effects of oral administration of spermine on the development of small intestine and growth performance of weaned pigs, J Anim Vet Adv. 11: 2782-2787.

142.Hou YQ*, Wang L, Ding BY, Liu YL, Zhu HL, Liu J, Li YT, Kang P, Yin YL, Wu G (2011) α-Ketoglutarate and intestinal function. Front Biosci (Landmark Ed). 16:1186-1196.

143.Hou YQ*, Yao K, Wang L, Ding BY, Fu DB, Liu YL, Zhu HL, Liu J, Li YT, Kang P, Yin YL, Wu GY (2011) Effects of a-ketoglutarate on energy status in the intestinal mucosa of weaned piglets chronically challenged with lipopolysaccharide. Br J Nutr. 106: 357-363.

144.Che ZQ, Liu YL, Wang HR, Zhu HL,Hou YQ, Ding BY (2011) The Protective Effects of Different Mycotoxin Adsorbents against Blood and Liver Pathological Changes Induced by Mold-contaminated Feed in Broilers. Asian-Australas J Anim Sci. 24: 250-257.

145.Liu YL, Meng GQ, Wang HR, Zhu HL,Hou YQ, Wang WJ, Ding BY (2011) Effect of three mycotoxin adsorbents on growth performance, nutrient digestibility and meat quality in broilers fed mold-contaminated feed. Br Poult Sci . 52: 255-263.

146.Hou YQ*, Wang L, Ding BY, Liu YL, Zhu HL, Liu J, Li YT, Wu X, Yin YL, Wu G (2010) Dietary α-ketoglutarate supplementation ameliorates intestinal injury in lipopolysaccharide-challenged piglets. Amino Acids. 39:555-564.

147.Kang P, Xiao HL,Hou YQ*, Ding BY, Liu YL, Zhu HL, Hu QZ, Hu Y, Yin YL (2010) Effects of astragalus polysaccharides, achyranthes bidentata polysaccharides, and acantbepanax senticosus saponin on the performance and immunity in weaned pigs. Asian-Australas J Anim Sci. 21:750-756.

148.Wu X, Ruan Z, Gao YL, Yin YL, Zhou XH, Wang L, Geng MM,Hou YQ, Wu G (2010) Dietary supplementation with L-arginine or N-carbamylglutamate enhances intestinal growth and heat shock protein-70 expression in weanling pigs fed a corn- and soybean meal-based diet. Amino Acids. 39:831-839.

149.Wu X, Yin YL, Li TJ, Wang L, Ruan Z, Liu ZQ,Hou YQ(2010) Dietary protein, energy and arginine affect LAT1 expression in forebrain white matter differently. Animal. 4: 1518-1521.

150.Liu YL, Shi JX, Lu J, Che ZQ, Zhu HL,Hou YQ, Yin YL, Zhao SJ, Ding BY, Liu HM (2010) Up-regulated expression of the peroxisome proliferator-activated receptor γ in hypothalamic-pituitary-adrenal axis of weaned pigs after Escherichia coli lipopolysaccharide challenge. Vet J . 184:230-235.

151.Fan W, Liu YL, Wu ZF, Hong Y, Zhu HL,Hou YQ, Yin YL, Han J (2010) Effects of rosiglitazone, an agonist of the peroxisome proliferator-activated receptor gamma, on intestinal damage induced by Escherichia coil lipopolysaccharide in weaned pigs. Am J Vet Res. 71 (11):1331-1338.

152.Yin YL,Huang RL,Li TJ,Ruan Z,Xie MY,Deng ZY,Hou YQ,Wu G(2010) Amino acid metabolism in the portal-drained viscera of young pigs: effects of dietary supplementation with chitosan and pea hull.Amino Acids.39 (5):1581-1587.

153.Deng J,Wu X,Bin S,Li TJ,Huang R,Liu Z,Liu Y,Ruan Z,Deng Z,Hou YQ,Yin YL(2010) Dietary amylose and amylopectin ratio and resistant starch content affects plasma glucose, lactic acid, hormone levels and protein synthesis in splanchnic tissues.J Anim Physiol Anim Nutr (Berl).94(2): 220-226.

154.FangJ,YanFY,KongXF,RuanZ,LiuZQ,HuangRL,LiTJ,GengMM,YangF,ZhangYZ,LiP,GongJoshua,WuGY,FanMZ,LiuYL,HouYQ, Yin YL (2009) Dietary supplementation with Acanthopanax senticosus extract enhances gut health in weanling piglets.Livest Sci. 123: 268-275.

155.Yin FG, Liu YL, Yin YL, Kong XF, Huang RL, Li TJ, Wu GY,Hou YQ(2009) Dietary supplementation with Astragalus polysaccharide enhances ileal digestibilities and serum concentrations of amino acids in early weaned piglets. Amino Acids. 37: 263-270.

156.Wang WC, Shi CY, Zhang JS, Gu WT, Li TJ, Gen MM, Chu WY, Huang RL, Liu YL,Hou YQ, Li P, Yin YL (2009) Molecular cloning, distribution and ontogenetic expression of the oligopeptide transporter PepT1 mRNA in Tibetan suckling piglets. Amino Acids. 37:593-601.

157.Liu YL, Shi JX, Lu J, Meng GQ, Zhu HL,Hou YQ, Yin YL, Zhao SJ, Ding BY (2009) Activation of peroxisome proliferator-activated receptor γ potentiates pro-inflammatory cytokine production, and adrenal and somatotropic changes of weaned pigs after Escherichia coli lipopolysaccharide challenge. Innate Immun. 15:169-178.

158.Li LL, Wu X, Peng HZ, Fan MZ, Hou ZP, Kong X F, Yin YL, Zhang B, Li TJ,Hou YQ, Yang K M, Li A K, Liu CY, Qiu X M, Liu YL (2009) The effect of dietary addition of a polysaccharide fromAtractylodes macrophalaKoidz on growth performance, immunoglobulin concentration and IL-1β expression in weaned piglets. J Agr SCI-Cambridge. 147:625-631.

159.Kong XF, Yin F, He Q, Liu H, Li T, Huang R, Fan M, Liu Y,Hou YQ, Li P (2009) Acanthopanax senticosus extract as a dietary additive enhances the apparent ileal digestibility of amino acids in weaned piglets. Livest Sci. 123:261-267.

160.Han J, Liu YL, Fan W, Chao J,Hou YQ, Yin YL, Zhu HL, Meng GQ, Che ZQ (2009) Dietary L-arginine supplementation alleviates immunosuppression induced by cyclophosphamide in weaned pigs. Amino Acids. 37:643-651.

161.Chen LX, Li P, Wang JJ , Li XL, Gao HJ, Yin YL,Hou YQ, Wu GY (2009) Catabolism of nutritionally essential amino acids in developing porcine enterocytes.Amino Acids. 37:143-152.

162.Yin FG, Yin YL, Kong XF, Liu YL, He QH, Li TJ, Huang RL,Hou YQ, Shu XG, Tan LX, Chen LX, Gong JH, Kim SW, Wu GY (2008) Dietary supplementation with Acanthopanax senticosus extract modulates gut microflora in weaned piglets. Asian-Australas J Anim Sci. 21(9):1330-1338.

163.Wu X, Ruan Z, Zhang YG,Hou YQ, Yin YL, Li TJ, Huang RL, Chu WY, Kong XF, Gao B, Chen LX (2008) True digestibility of phosphorus in different resources of feed ingredients in growing pigs. Asian-Australas J Anim Sci, 21:107-119.

164.Liu YL, Huang JJ,Hou YQ, Zhu HL, Zhao SJ, Ding BY, Yin YL, Yi GF, Shi JY, Fan W (2008) Dietary arginine supplementation alleviates intestinal mucosal disruption induced by Escherichia coli lipopolysaccharide in weaned pigs. Br J Nutr. 100:552-560.

165.Liu YL, Lu J, Shi JX,Hou YQ, Zhu HL, Zhao SJ, Liu HM, Ding BY, Yin YL, Yi GF (2008) Increased expression of the peroxisome proliferator-activated receptor γ in the immune system of weaned pigs after Escherichia coli lipopolysaccharide challenge.Vet Immunol Immunop. 124:82-92.

166.Guo GL, Liu YL, Fan W, Han J,Hou YQ, Yin YL, Zhu HL, Ding BY, Shi JX, Lu J, Wang HR, Chao J, Qu YH (2008) Effects of achyranthes bidentata polysaccharide on growth performance, immunological, adrenal, and somatotropic responses of weaned pigs challenged with Escherichia coli lipopolysaccharide. Asian-Australas J Anim Sci. 21:1189-1195.

167.Liu YL,Yi GF,Song GL,Hou YQ,Huang JW,Vázquez-Añón M,Knight CD(2007) Impact of feeding 2-hydroxy-4-(methylthio) butanoic acid and DL-methionine supplemented maize-soya bean-rapeseed meal diets on growth performance and carcass quality of broilers.Br Poult Sci. 48:190-197.

168.Liu YL,Song GL,Yi GF,Hou YQ,Huang JW,Vázquez-Añón M,Knight CD(2006) Effect of supplementing 2-hydroxy-4-(methylthio) butanoic acid and dl-methionine in corn-soybean-cottonseed meal diets on growth performance and carcass quality of broilers.Asian-Australas J Anim Sci. 19:1197-1205.

169.Hou YQ, Liu YL, Hu J, Shen WH (2006) Effects of lactitol and tributyrin on growth performance, small intestinal morphology and enzyme activity in weaned pigs. Asian-Australas J Anim Sci. 19:1470-1477.

代表性科研项目

1.国家自然科学基金区域联合创新发展基金:仔猪肠道损伤的营养修复机制研究(U22A20514,2022):258万

2.国家重点研发计划“十四五”课题任务:靶向仔猪肠道健康营养调控产品研制(2022YFD1300403,2022):30万

3.国家自然科学基金面上项目:精氨酸和脯氨酸代谢在PEDV感染仔猪小肠损伤中的作用及营养调控(2021):58万

4.技术创新专项重大项目:基于多组学技术的仔猪肠道功能营养调控剂筛选与产品开发(2019):200万

5.2017中央引导地方科技发展资金:湖北省动物营养与肠道健康创新平台建设(2017):200万

6.“十三五”子项目:畜禽应激综合症防控技术研究(2016):425万

7.国家自然科学基金面上项目:Ⅰ型干扰素信号通路在N-乙酰半胱氨酸抗仔猪流行性腹泻病毒感染中的作用研究(2016):25万

8.中组部“万人计划”百千万工程领军人才项目(2016):100万

9.农业部全国农业杰出科研人才项目(2015):100万

10.湖北省重大科技创新计划:新型饲料产品开发——猪禽饲料中抗生素替代品的研究与示范应用(2014):150万

11.国家自然科学基金面上项目:EGFR和mTOR信号通路在N-乙酰半胱氨酸调控仔猪小肠功能中的作用研究(2013):75万

12.湖北省自然科学基金重点项目:天然植物精油对猪肠道健康的调控作用机制(2013):10万

13.湖北省重大人才项目:湖北省高端人才引领培养计划(2012):150万

14.国家973计划课题:猪肠道屏障功能营养调控的关键分子机制研究(2012):75万

15.“十二五”农村领域国家科技计划课题子课题项目:饲用乳酸菌标准化检测技术研究(2012):25万

16.国家农业科技成果转化资金:功能环保型水禽专用预混料生产技术与产品中试示范(2011):60万

17.湖北省研究与开发计划项目:新型饲用益生菌、粘附素及酶制剂的研究与开发(2010):50万

18.湖北省自然科学基金重点项目:畜禽肠道功能的营养调控及其应用研究(2010):20万

19.湖北省自然科学科学基金重点项目:断奶应激对仔猪肠黏膜细胞能量代谢的影响的研究(2009):10万

20.武汉市学科带头人计划项目:N-乙酰半胱氨酸对断奶仔猪免疫应激与肠道屏障功能的调控作用及其分子机制(2009):10万

21.国家自然科学基金:α-酮戊二酸调控断奶仔猪小肠黏膜屏障功能的分子机理研究(2008):30万

22.国家农业科技成果转化资金:畜禽肉质改进技术与产品开发中试示范(2008):70万

23.湖北省自然科学基金计划创新群体项目:营养调控仔猪肠道发育与免疫屏障功能的研究(2007):40万

主要奖励

1.2010年国家科技进步二等奖仔猪肠道健康调控关键技术及其在饲料产业化中的应用(排2)

2.2023年湖北省高等学校教学成果一等奖基于新农科理念的智能化饲料工程人才培养体系构建与实践(排1)

3.2018年湖北省高等学校教学成果一等奖动物科学专业“卓越饲料工程师”培养的研究与实践(排1)

4.2017年湖北省技术发明一等奖基于猪肠道功能靶标的饲料添加剂研制与应用(排1)

5.2011年湖北省科技进步一等奖仔猪生理机能营养调控与饲料产业化关键技术(排1)

6.2009年湖南省科技进步一等奖仔猪肠道健康及功能性饲料研究与应用(排6)

7.2009年湖北省科技进步二等奖功能性饲料蛋白资源的生产技术研究与产品开发(排2)

8.2008年湖北省科技进步二等奖畜禽肉质改进技术的研究与产品开发(排1)

9.2004年湖北省科技进步二等奖植物提取物饲料添加剂的研究与开发(排1)

10.2006年湖北省科技进步三等奖ω-3多不饱和脂肪酸鸡蛋饲粮研究(排2)

11.2005年湖北省科技进步三等奖功能性蛋白源—血浆蛋白粉的研究与开发(排2)

代表性发明专利

侯永清,易丹,丁斌鹰,吴涛,胡群兵.一种猪干扰素诱导剂及其制备方法和用途(ZL201711497883.1)

侯永清,易丹,丁斌鹰;吴涛,胡群兵.油脂组合物在制备猪禽饲料添加剂上的用途、饲料添加剂及饲料(ZL201711498170.7)

侯永清,易丹,吴涛,丁斌鹰.一种抗猪流行性腹泻病毒感染的组合物及其应用(ZL201910755961.6)

侯永清,吴涛,易丹,丁斌鹰.葛根素在制备防治猪病毒感染的药物中的用途、防治猪病毒感染的药物及猪饲料添加剂(ZL201711498123.2)

侯永清,吴涛,易丹,丁斌鹰.一种猪肠道损伤的检测试剂盒及检测方法(ZL201711498150.X)

侯永清,吴涛,易丹,丁斌鹰.一种猪干扰素诱生剂的筛选方法(ZL201711498133.6)

侯永清,丁斌鹰.一种抗菌饲料添加剂与应用(ZL201410538115.6)

侯永清,吴涛,丁斌鹰,易丹,赵迪.一种N-乙酰-L-半胱氨酸在制备治疗或预防猪病毒感染药物中的应用(ZL 201410726587.4)

侯永清,丁斌鹰,张开诚.一种辛酸乳酸甘油酯饲料添加剂的制备方法和应用(ZL201410771025.1)

侯永清,丁斌鹰,易丹.一种筛选益生菌的方法(ZL201310037320.X)

侯永清,丁斌鹰,刘玉兰.一种增进畜禽肠道屏障功能的饲料添加剂及其应用(ZL201310037355.3)

侯永清,吴涛,窦茂鑫,赵迪,丁斌鹰.一种表达猪胰高血糖素样肽-2的重组嗜酸乳杆菌的构建方法及用途(ZL201310037473.4)

侯永清,吴涛,窦茂鑫,赵迪,丁斌鹰.一种表达猪表皮生长因子的重组嗜酸乳杆菌的构建方法及用途(ZL201310038835.1)

侯永清,丁斌鹰.一种复合型天然植物饲料添加剂与应用(ZL201310037416.6)

侯永清,丁斌鹰.三乳酸甘油酯作为饲料酸化剂的应用(ZL201310039966.1)

侯永清,丁斌鹰,张开诚.乳酸丁酸甘油酯作为饲料添加剂的应用(ZL201310039695.X)

侯永清,丁斌鹰.一种包被的天然植物精油饲料添加剂及其应用(ZL201310038833.2)

侯永清,丁斌鹰,易丹.一种合生素饲料添加剂(ZL200710053206.0)

侯永清,丁斌鹰,朱惠玲.一种畜禽肉质改进剂(ZL200710168519.0)

侯永清,丁斌鹰,刘玉兰.一种增进畜禽肠道生理功能的饲料添加剂(ZL200710053205.6)

侯永清,王春维,朱惠玲,丁斌鹰,房桂兵.植物提取物饲料添加剂(ZL03125209.5)

侯永清.三丁酸甘油酯作为饲料添加剂的应用(ZL03128368.3)

吴涛,侯永清,丁斌鹰,易丹.赵迪.新生仔猪肠道正常健康功能菌群早期建立方法(ZL201711498054.5)

吴涛,侯永清,赵迪,丁斌鹰,易丹,王蕾,陈洪波.用于饲料中添加的双歧杆菌的快速定性、定量检测试剂盒及检测方法和应用(ZL201510856101.3)

吴涛,侯永清,赵迪,丁斌鹰,易丹,王蕾,陈洪波.用于饲料中添加的嗜酸乳杆菌的快速定性、定量检测试剂盒及检测方法和应用(ZL201510860823.6)

吴涛,侯永清,赵迪,丁斌鹰,易丹,王蕾,陈洪波.用于饲料中添加的屎肠球菌的快速定性、定量检测试剂盒及检测方法和应用(ZL201510854914.9)

吴涛,侯永清,赵迪,丁斌鹰,易丹,王蕾,陈洪波.用于饲料中添加的粪肠球菌的快速定性、定量检测试剂盒及检测方法和应用(ZL201510860782.0)

吴涛,侯永清,赵迪,丁斌鹰,易丹,王蕾,陈洪波.用于饲料中添加的植物乳杆菌的快速定性、定量检测试剂盒及检测方法和应用(ZL201510854975.5)

吴涛,侯永清,赵迪,丁斌鹰,易丹,王蕾,陈洪波.用于饲料中添加的保加利亚乳杆菌的快速定性、定量检测试剂盒及检测方法和应用(ZL201510854943.5)

吴涛,侯永清,赵迪,丁斌鹰,易丹,王蕾,陈洪波.用于饲料中添加的干酪乳杆菌的快速定性、定量检测试剂盒及检测方法和应用(ZL201510856158.3)

丁斌鹰,侯永清,严念东.稻谷专用复合酶饲料添加剂(ZL200710053204.1)

王春维,侯永清,舒夏娃,丁斌鹰,朱惠玲,李建文,房桂兵,刘昌杜.功能性饲料蛋白肠膜蛋白粉的制备方法(ZL200710168967.0)

(更新至2023.7.14)

上一篇:印遇龙院士

下一篇:刘玉兰教授